This authoritative reference presents the latest research on the role of chemokines, chemokine receptors, and genetic variability in the susceptibility, prevention, and treatment of HIV-1 - exploring new therapeutic strategies for improved treatment of HIV-1 infected patients by blocking chemokine receptor expression. With contributions from seasoned experts in the field, "Chemokine Receptors and AIDS" details the role of chemokine receptors in HIV-1 infection and pathogenesis; the identification and role of the CCR5-D32 allele in HIV infection; potential novel methods to treat HIV-1 infection by blocking or down-regulating the CCR5 and CXCR4 HIV-1 coreceptors strategies using monoclonal antibodies, small molecules, and ribosymes and more! Offering more than 1200 current references, this book is an essential reference for infectious disease specialists, epidemiologists, virologists, immunologists, pharmacologists, medicinal chemists and biochemists, microbiologists, and medical students in these disciplines.
